When trillion‑member libraries meet physics: what diversity really means

By Pharmaceutical Technology | January 20, 2026

Dr Karsten Eastman, CEO, Sethera Therapeutics, highlights the challenges around ‘true’ diversification in DNA libraries.

In drug discovery, big numbers for screening campaigns are loved. Trillions of molecules! 1020‑member libraries! But there is a very real question to ask: how many distinct molecules can actually fit in a tube?

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